10 Best Supplements To Gain Muscle Mass in 2026

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For serious muscle gains, NAKED Mass Natural Weight Gainer takes the top spot because it delivers 1,250 calories and 50g of protein from just three clean ingredients, whey, casein, and organic tapioca maltodextrin. If you need even more density, the Dymatize Super Mass Gainer packs 1,280 calories with added creatine. The Optimum Nutrition Serious Mass is our pick for dedicated bulking phases.

The challenge with muscle mass supplements isn’t finding calories, it’s finding calories that don’t leave you feeling bloated or loaded with artificial fillers. Hard gainers and serious lifters need a formula that fits their daily intake goals without compromising on protein quality or ingredient transparency.

This guide is built on manufacturer specifications, expert round-ups, and patterns in owner feedback across the top mass gainers and muscle builders. We highlight what each product does best so you can match a supplement to your specific weight gain strategy.

Top 10 Supplements To Gain Muscle Mass in the Market

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The Best Supplements To Gain Muscle Mass, Reviewed

#1Best Overall

NAKED Mass Natural Weight Gainer

NAKED Mass Natural Weight Gainer
Calories per serving1,250
Protein per serving50g
Carbs per serving252g
IngredientsWhey, casein, organic tapioca maltodextrin
CertificationsNSF Certified, GMO Free, Gluten Free, Soy Free
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What We Like

  • 1,250 calories per serving for serious bulking
  • 50g protein with fast and slow release
  • Only three ingredients: whey, casein, organic tapioca maltodextrin

Trade-offs

  • Unflavored means you'll need to mix with extras
  • Unflavored, so you'll need to add flavor yourself

A single serving delivers 1,250 calories, 50 grams of protein, and 252 grams of carbs from just three ingredients, whey, casein, and organic tapioca maltodextrin. That makes it a straightforward option for anyone who wants to pack on mass without guessing what’s inside their shake.

The trade-off is that it’s unflavored, which means you’ll want to blend it with fruit, peanut butter, or milk to make it taste good, plain mixed with water can be a chore. Compared to Dymatize Super Mass Gainer, which offers 1,280 calories, 52g protein, and 245g carbs per serving, Naked Mass uses a simpler ingredient list but requires you to add your own flavor. If you don’t mind mixing your own flavors and want a clean, minimal-ingredient mass gainer, this is the one.

Best for: Hard gainers who want a clean, high-calorie mass gainer with minimal ingredients and NSF Certification. Not ideal for those who prefer a pre-flavored shake ready to drink straight from the tub.

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#2Best High-Calorie Gainer

Dymatize Super Mass Gainer

Dymatize Super Mass Gainer
Calories per serving1,280
Protein per serving52g
Carbs per serving245g
Creatine per serving1g
Protein sourcesWhey + Casein
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What We Like

  • High 52g protein per serving
  • 1,280 calories for mass gain
  • Fast- and slow-digesting protein blend
  • Includes 1g creatine per serving

Trade-offs

  • Only 8 servings per 6 lb container
  • Creatine dose is low at 1g per serving

With 1,280 calories and 52 grams of protein per serving, this is built for anyone who struggles to eat enough to add serious size. The blend of fast-digesting whey and slow-digesting casein means your muscles get a steady stream of amino acids over hours, not just a quick spike. That sustained delivery supports muscle growth and recovery for long-lasting results, which is exactly what you need when your goal is packing on pounds. It also includes 1 gram of creatine and a handful of vitamins, so you are covering a few extra bases without another tub on the shelf.

Portion size is the trade-off: each serving packs 245 grams of carbs and 1,280 calories, so mixing a full serving can feel like a meal in a glass. If you are not used to that density, it might sit heavy or take effort to finish. Compared to NAKED Mass Natural Weight Gainer, which also offers 1,250 calories per serving, this Dymatize option includes added creatine and a blend of whey and casein. For the lifter who wants maximum calories and protein in minimal servings, this is a straightforward tool. Just know the container provides 8 servings.

Best for: Hardgainers and athletes needing a dense, high-calorie shake to push past a weight plateau.

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#3Best For Bulking

Optimum Nutrition Serious Mass

Optimum Nutrition Serious Mass
Calories per serving1,200+ calories
Protein per serving50g
Carbohydrates per serving250g+
Key added ingredientsCreatine, Glutamine, BCAAs
Vitamins & minerals20+ essential
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What We Like

  • 1,200+ calories per serving for bulking
  • 50g protein blend supports muscle repair
  • 250g+ carbs replenish glycogen stores

Trade-offs

  • 2-scoop serving requires blending for best taste
  • Weight gainer, not a lean muscle formula

Over 1,200 calories per two-scoop serving make this a serious tool when your appetite can’t keep up with your goals. The 20-plus vitamins and minerals also help cover nutritional gaps, so you’re not just adding mass but supporting recovery and immune function along the way. This is a mass gainer for anyone who has tried eating more and still struggles to tip the scale upward.

Serious Mass delivers over 250 grams of carbohydrates per serving, which works great for hardgainers and high-volume trainers but feels heavy if you’re watching your carb intake or prefer a leaner gainer. Compared to the Dymatize Super Mass Gainer, which also packs around 1,280 calories, Serious Mass offers a slightly higher carb count and a broader vitamin profile. That makes it the more nutritionally complete option for a dedicated bulk. Just plan to blend it with milk or fruit, because drinking two scoops with water alone can be a thick, sweet commitment.

Best for: Anyone in a serious bulking phase who needs high calories, carbs, and added nutrients to gain weight fast. Not ideal for low-carb dieters or those seeking a lean, low-sugar mass gainer.
#4Best 2-in-1 Muscle Builder

MuscleTech Nitro-Tech Whey Protein

MuscleTech Nitro-Tech Whey Protein
Protein Per Serving30g
Creatine Per Serving3g
BCAAs Per Serving6.6g
Scoops Per Tub40
Key IngredientWhey Protein Isolate
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What We Like

  • 30g protein plus 3g creatine per scoop
  • Clinically shown to build 8.8 lbs lean muscle in 6 weeks
  • Micro-filtered to remove fat and carbs
  • Enzyplex enzyme complex aids protein digestion

Trade-offs

  • Only 40 scoops per tub means fewer servings than some competitors
  • Contains creatine, so not ideal for those avoiding it
  • Requires consistent daily use for 6 weeks to see clinical results

A single scoop delivers 30g of whey protein isolate plus 3g of creatine and 6.6g of BCAAs, so you get two muscle-building ingredients without mixing separate powders. Clinical data shows users adding 8.8 pounds of lean muscle over six weeks, which is 70% better than ordinary whey alone. The micro-filtration strips out excess fat and carbs, and the added Enzyplex enzyme blend helps your stomach handle the protein load more comfortably.

The tub holds 40 scoops, so you’ll need to plan your usage if you train daily. Clinical results are based on six weeks of consistent use, so this rewards patience rather than promising overnight changes. It’s a good fit for lifters who want a lean protein-plus-creatine combo without extra calories from a weight gainer.

Best for: Lifters who want a protein powder with built-in creatine for lean muscle gain and don't mind fewer servings per container. Not ideal for those who prefer a calorie-dense mass gainer or want to avoid creatine.

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#5Best Whole-Food Ingredient Blend

Mutant Mass Extreme Gainer

Mutant Mass Extreme Gainer
Calories per serving1,100
Protein per serving56 g
Protein blendWhey isolate, concentrate, casein
Whole-food ingredientsBarley, sweet potato, oats, avocado, coconut oil, flaxseed, pumpkin seed, sunflower oil
Servings per pouch16
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What We Like

  • 56 g protein from whey isolate, concentrate, and casein
  • 1,100 calories per serving supports weight gain
  • Whole-food ingredients like barley, sweet potato, and oats
  • 26.1 g EAAs and 12.2 g BCAAs per serving

Trade-offs

  • Only 16 servings per pouch means frequent repurchasing
  • Single flavor option limits taste variety

Fifty-six grams of protein per serving from a blend of whey isolate, concentrate, and casein gives you both fast and slow-digesting amino acids, which helps keep your muscles fed for hours after a shake. The 1,100 calories come partly from whole-food sources like barley, sweet potato, rolled oats, avocado, coconut oil, flaxseed, pumpkin seed, and sunflower oil, so you’re getting micronutrients and fiber alongside the macros. That makes this a smart pick if you want a mass gainer that feels closer to real food than a bag of powdered sugar.

Each 2.2 lb pouch delivers 1,100 calories and 56 g of protein per serving, but you get only 16 servings total. So you’ll be ordering more often than with a larger tub like Optimum Nutrition Serious Mass. The triple chocolate flavor is the only option listed, which limits variety for those who prefer other tastes. Still, for someone who values whole-food ingredients like barley, sweet potato, and rolled oats, plus a protein blend that combines whey isolate, whey concentrate, and casein, this gainer covers both immediate and sustained release.

Best for: Athletes who want a calorie-dense mass gainer built from whole-food ingredients and a multi-source protein blend. Not ideal for those who prefer a larger number of servings per container or a wider flavor choice.

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#6Best Lactose-Free Option

MuscleMeds CARNIVOR Beef Protein

MuscleMeds CARNIVOR Beef Protein
Protein per serving23g
Servings per container56
SourceBeef protein isolate
Key labelsLactose free, sugar free, fat free
CertificationHalal certified
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What We Like

  • Lactose free and sugar free
  • 23g protein per serving from beef protein isolate

Trade-offs

  • No added carbs or calories for bulking
  • Not suitable for those needing carb-heavy mass gainers

This makes it a smart pick if dairy-based whey leaves you bloated or uncomfortable, especially when you are just starting out and figuring out what your gut can handle.

This is a straight protein supplement, not a mass gainer. If your goal is to pack on serious size quickly, you will need to add your own calories from food or choose a product designed for that purpose. Carnivor Beef Protein works best as a clean, everyday recovery tool for lifters who want the muscle-building aminos without the dairy or the sugar crash.

Best for: People who want a lactose-free, sugar-free protein from beef isolate for muscle building. Not ideal for those needing a high-calorie mass gainer in a single scoop.
#7Best Low Sugar Protein Blend

BSN SYNTHA-6 Edge Protein

BSN SYNTHA-6 Edge Protein
Protein Per Serving24g
Protein SourcesHydrolyzed whey, isolate, concentrate, micellar casein
BCAAs & EAAs11g naturally occurring
Servings Per Container48
Flavor ProfileCreamy, milkshake-like texture
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What We Like

  • Low sugar formula for keto dieters
  • Multi-source protein for sustained release
  • 11g naturally occurring BCAAs per serving
  • Versatile any-time-of-day use

Trade-offs

  • Only 24g protein per serving for mass goals
  • Lower calorie count than mass gainers

Twenty-four grams of protein from a six-source matrix, hydrolyzed whey, whey isolate, concentrate, calcium caseinate, micellar casein, and milk protein concentrate, means your muscles get both fast and slow-digesting amino acids. That blend supports recovery right after a workout and keeps feeding your muscles for hours, all while keeping sugar low enough for a keto-friendly diet. This is the protein for someone who wants a clean, creamy shake without the carb crash, perfect as a between-meal snack or post-gym staple when you are not trying to force down a thousand calories.

At 24 grams of protein per serving, Syntha-6 Edge sits squarely in the standard protein range, not the mass-gainer category. If your goal is rapid weight gain with maximum calories, Dymatize Super Mass Gainer delivers 52 grams of protein and 1,280 calories per serving. But for anyone who wants a low-sugar, versatile protein with a creamy texture that fits into a balanced diet, this blend works well for daily recovery and muscle support.

This protein is best suited for lifters who want a low-sugar, multi-source protein for daily recovery and between-meal use. It is not ideal for those needing high-calorie mass gain or a higher protein dose per serving, since it provides only 24 grams of protein and a lower calorie count compared to mass gainers.

#8Best With Creatine

MuscleTech 100% Mass Gainer

MuscleTech 100% Mass Gainer
Calories per serving1,500
Protein per serving60g
CreatineHPLC-tested creatine monohydrate
Carbs per serving304g
BCAAs per serving13g+
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What We Like

  • 60g protein and 1,500 calories per serving
  • Includes HPLC-tested creatine monohydrate
  • 6.3g L-leucine per serving
  • Vanilla Milkshake flavor from top flavor houses

Trade-offs

  • 6-scoop serving size requires mixing with skim milk
  • Not suitable for those avoiding artificial sweeteners.

A single serving delivers 1,500 calories and 60 grams of protein when mixed with skim milk, making it one of the densest mass gainers you can scoop. That calorie load means you can hit a serious surplus without having to choke down multiple shakes a day, which is exactly what someone trying to add size quickly needs. The creatine monohydrate here is HPLC-tested, and studies indicate it helps replenish ATP stores for better performance and strength gains over time.

Each serving takes six scoops and requires two cups of skim milk, so you are committing to a fairly thick, heavy shake. If you compare it to a leaner option like Rival Nutrition Clean Gainer, which offers 550 calories per serving, this one is clearly built for aggressive bulking rather than a moderate surplus. For anyone who struggles to eat enough and wants the added creatine boost without buying a separate supplement, this tub does the heavy lifting in one drink.

Best for: Anyone who wants a calorie-dense, creatine-infused mass gainer to support rapid muscle growth and strength gains. Not ideal for those seeking a lower-carb or lighter-calorie option.

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#9Best Clean Ingredient Gainer

Rival Nutrition Clean Gainer

Rival Nutrition Clean Gainer
Calories per serving550
Protein per serving30g
Carbs per serving97g
SweetenerStevia leaf extract
FlavorCinnamon Toast Cereal
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What We Like

  • Naturally flavored, no artificial dyes
  • Sweetened with stevia, no added sugars
  • 30g protein from whey, milk, casein
  • 97g multi-source carbs from quinoa, blueberry

Trade-offs

  • 550 calories per serving is a moderate gainer
  • Only 2g added sugars limits taste sweetness

At 550 calories and 30 grams of protein per serving, this gainer keeps the focus on clean ingredients without packing in filler calories. The protein blend draws from whey, milk, and micellar casein, which means your body gets a steady release of amino acids over time. That matters when you are trying to add lean mass without the bloated feeling some heavy gainers leave behind. The multi-source carbs come from quinoa, blueberry, and oat fiber, not just cheap maltodextrin, so you are fueling recovery with real food sources. This one suits anyone who wants a straightforward, no-junk option that still delivers solid macros for muscle growth.

Five hundred fifty calories per serving is on the lighter end for serious bulkers. If your goal is to pack on size quickly and you need a denser calorie load, other gainers on the market offer more calories per serving. But for the lifter who prefers natural flavors, stevia sweetness, and a clean ingredient list that skips artificial dyes and fillers, Rival Nutrition Clean Gainer hits a sweet spot. It mixes easily with cold water or milk, so you are not stuck blending a thick sludge post-workout. Best for the person who values ingredient quality over sheer calorie count.

Best for: Lifters who want a clean, naturally sweetened gainer with moderate calories and real food carb sources. Not ideal for those needing a high-calorie bulk in minimal shakes.

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#10Best Low Carb Mass Gainer

Insane Labz Insane Whey Mass Gainer

Insane Labz Insane Whey Mass Gainer
Protein per serving25g
Carbs per serving5g
Sugar per serving1g
Flavors available5 flavors
Banned substance statusWADA approved
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What We Like

  • Only 5g carbs per serving
  • WADA approved for athletes
  • Naturally occurring BCAA profile
  • No-clumps guarantee on mixability

Trade-offs

  • Lower calorie count than traditional mass gainers
  • Single protein source limits variety

25 grams of protein with just 5 carbs and 1 gram of sugar makes this a standout option if you want muscle gains without the heavy carb load. It fits neatly into a lower-carb or keto-friendly approach, and the WADA approval means competitive athletes can use it without worry. The five flavor choices and no-clumps guarantee take the hassle out of mixing, so you can focus on recovery rather than fighting with a shaker bottle.

This is a leaner gainer, not the kind you grab when you need to pack on mass fast with high calorie counts. Compared to the Dymatize Super Mass Gainer, which delivers 52g of protein and 245g carbs per serving, Insane Whey is better suited for someone who wants controlled, steady muscle building without the sugar spike. It does one thing well, but if you are chasing extreme bulk, you will want a heavier option.

Best for: Athletes and fitness enthusiasts who want lean muscle gains with minimal carbs and sugar. Not ideal for those needing high-calorie mass building or a multi-source protein blend.

How We Evaluated Supplements To Gain Muscle Mass

We started by examining the nutrition profiles of each mass gainer, total calories per serving, protein content, carb-to-fat ratio, and the specific protein sources used. Manufacturer data gave us the baseline for ingredients like whey isolate, casein, and added creatine. We also reviewed expert commentary on which protein blends support sustained muscle repair versus quick calorie spikes.

Three criteria mattered most for this category. First, caloric density, a true mass gainer needs enough calories per serving to meaningfully support a surplus. Second, protein quality and blend, fast- and slow-digesting proteins like whey and casein provide a longer window for muscle repair. Third, ingredient transparency, we favored products with fewer artificial additives, natural sweeteners, and clear labeling on carb sources.

A research-led evaluation has limits. We don’t test these products in a lab or track individual results. What we can do is compare published specs against common owner experiences, like mixability, taste complaints, and reported digestive comfort, to give you a reliable starting point for your own trial.

What To Look For In Supplements To Gain Muscle Mass

Choosing a mass gainer means balancing calorie goals, protein quality, and ingredient simplicity. The right supplement fits your daily surplus without forcing you to choke down a shake that feels like a chemistry experiment.

Look for a mass gainer with a high calorie count per serving if you’re in a serious bulk. You want 40-50g of protein from a blend of fast and slow sources. Clean ingredients without artificial dyes or excessive added sugars are also important.

Calories Per Serving

The whole point of a mass gainer is to make hitting a calorie surplus easier. Most serious options land between 1,250 and 1,500 calories per serving. If you’re a hard gainer who struggles to eat enough whole food, a higher-calorie formula like the MuscleTech 100% Mass Gainer at 1,500 calories can close that gap fast. For lighter maintenance or lean bulking, a moderate gainer around 550 calories may be more practical. Match the serving size to your current intake, a high-calorie shake is wasted if you can only stomach half.

Protein Source and Blend

A single protein source digests quickly and may leave your muscles without sustained amino acids. The best mass gainers combine whey concentrate or isolate for fast absorption with casein for slow release, giving your body a steady supply of building blocks for hours. Check the protein-per-serving number too, 50g is a strong target for post-workout recovery, while 30g works better as a between-meal supplement. If you have lactose sensitivity, a beef protein isolate like the MuscleMeds CARNIVOR option avoids dairy entirely without sacrificing protein quality.

Carb Sources and Sugar Content

Carbs in mass gainers aren’t just filler, they replenish glycogen and drive calories upward. The best sources are complex carbs like oats, sweet potato, quinoa, or organic tapioca maltodextrin, which digest slower and cause fewer blood sugar spikes. Watch for products that rely on simple sugars or maltodextrin blends that can leave you feeling sluggish. If you’re on a low-carb or keto approach, a formula like the Insane Labz Insane Whey Mass Gainer keeps carbs at just 5g per serving, but you’ll need to get your calories from other meals.

  • Compare the serving size to your daily calorie target, a single shake should not replace an entire day’s food.
  • Look for a protein blend (whey + casein) rather than a single source for sustained amino acid delivery.
  • Check the carb source, whole-food ingredients like oats and quinoa beat processed maltodextrin.
  • Consider added extras like creatine or BCAAs if you want a multi-benefit formula in one scoop.
  • Read flavor reviews, unflavored powders like NAKED Mass require your own sweetener and milk.

A good rule of thumb: the fewer ingredients on the label, the easier it is to know exactly what you’re putting in your body.

Supplements To Gain Muscle Mass Compared

The table below compares the top mass gainers and muscle builders side by side so you can see calorie counts, protein content, and key features at a glance.

ProductCalories per servingProtein per servingProtein sources
NAKED Mass Natural Weight Gainer1,25050gWhey, casein
Dymatize Super Mass Gainer1,28052gWhey + Casein
Optimum Nutrition Serious Mass1,200+50gWhey protein
MuscleTech Nitro-Tech Whey ProteinN/A30gWhey Protein Isolate
Mutant Mass Extreme Gainer1,10056 gWhey isolate, concentrate, casein
MuscleMeds CARNIVOR Beef ProteinN/A23gBeef protein isolate
BSN SYNTHA-6 Edge ProteinN/A24gHydrolyzed whey, isolate, concentrate, micellar casein
MuscleTech 100% Mass Gainer1,50060gN/A
Rival Nutrition Clean Gainer55030gWhey, milk, micellar casein
Insane Labz Insane Whey Mass GainerN/A25gWhey protein

Frequently Asked Questions

How many calories should a muscle mass supplement have?

Most mass gainers range from 550 to 1,500 calories per serving. For serious bulking, look for a high calorie count to create a meaningful surplus. Lighter options work better for maintenance or lean gains.

Can you gain muscle without taking supplements?

Yes, whole foods for muscle growth like lean meats, eggs, dairy, beans, and grains provide everything your body needs. Supplements simply make it easier to hit high calorie and protein targets when appetite or convenience is a challenge.

What is the difference between a mass gainer and a protein powder?

Mass gainers pack significantly more calories per serving, often from carbs and fats, while standard protein powders focus on 20-30g of protein with minimal extras. Mass gainers are designed for weight gain; protein powders support muscle repair without the surplus.

Are mass gainers safe to take every day?

For most healthy adults, yes, as long as you account for the calories in your total daily intake. Over-relying on mass gainers without adjusting food portions can lead to excess fat gain. Treat them as a supplement, not a meal replacement.

Do I need creatine in my mass gainer?

Not necessarily, but it is convenient. Products like MuscleTech Nitro-Tech Whey Protein include 3g of creatine per scoop, which saves you buying a separate pre-workout supplement or creatine powder. If you already take creatine separately, a mass gainer without it gives you more flexibility.

The Bottom Line

The NAKED Mass Natural Weight Gainer is our best overall pick for hard gainers who want a clean, high-calorie formula with no artificial ingredients. Its three-ingredient label and 50g protein blend make it a straightforward choice for anyone ready to bulk without guessing what is in their shake.

If your goal is pushing past a stubborn plateau with maximum density, the Dymatize Super Mass Gainer delivers 1,280 calories and 52g protein per serving, plus a gram of creatine. For lifters who prefer a leaner, natural approach, the Rival Nutrition Clean Gainer offers moderate calories from real food carb sources with no artificial dyes.

The single most important factor is matching the serving size and calorie count to your daily surplus needs. A mass gainer that fits your appetite and schedule will always outperform one that sits unused in the cupboard.